Antiphospholipid antibody syndrome (APS), also called antiphospholipid syndrome, is an autoimmune condition in which certain antibodies are associated with an increased risk of blood clots and pregnancy complications. Symptoms may include deep vein thrombosis, pulmonary embolism, stroke, or recurrent pregnancy loss, although some people with antiphospholipid antibodies never develop the syndrome. Diagnosis involves assessing clinical history and blood tests for lupus anticoagulant, anticardiolipin antibodies, and anti-beta-2 glycoprotein I antibodies. Positive results may need confirmation at least 12 weeks later. Treatment depends on individual risk and may include anticoagulant medication under medical supervision. Have questions about APS testing, treatment options, or finding a qualified specialist? Share your questions to encourage an informed discussion.